Thursday, October 22, 2009

Here's the List. Don't Screw Up.

Doping in sport is pretty cut and dry, right? I mean, they either did it or didn't. WADA (World Anti-Doping Association) has released the 2010 Banned Substance list. Can you keep up? Here it is:

PROHIBITED SUBSTANCES
S1. ANABOLIC AGENTS
Anabolic agents are prohibited.
1. Anabolic Androgenic Steroids (AAS)
a. Exogenous* AAS, including:
1-androstendiol (5α-androst-1-ene-3β,17β-diol ); 1-androstendione (5α-
androst-1-ene-3,17-dione); bolandiol (19-norandrostenediol); bolasterone;
boldenone; boldione (androsta-1,4-diene-3,17-dione); calusterone;
clostebol; danazol (17α-ethynyl-17β-hydroxyandrost-4-eno[2,3-d]isoxazole);
dehydrochlormethyltestosterone (4-chloro-17β-hydroxy-17α-methylandrosta-
1,4-dien-3-one); desoxymethyltestosterone (17α-methyl-5α-androst-2-en-
17β-ol); drostanolone; ethylestrenol (19-nor-17α-pregn-4-en-17-ol);
fluoxymesterone; formebolone; furazabol (17β-hydroxy-17α-methyl-5α-
androstano[2,3-c]-furazan); gestrinone; 4-hydroxytestosterone (4,17β-
dihydroxyandrost-4-en-3-one); mestanolone; mesterolone; metenolone;
methandienone (17β-hydroxy-17α-methylandrosta-1,4-dien-3-one);
methandriol; methasterone (2α, 17α-dimethyl-5α-androstane-3-one-17β-ol);
methyldienolone (17β-hydroxy-17α-methylestra-4,9-dien-3-one); methyl-1-
testosterone (17β-hydroxy-17α-methyl-5α-androst-1-en-3-one);
methylnortestosterone (17β-hydroxy-17α-methylestr-4-en-3-one);
methyltestosterone; metribolone (methyltrienolone, 17β-hydroxy-17α-
methylestra-4,9,11-trien-3-one); mibolerone; nandrolone; 19-
norandrostenedione (estr-4-ene-3,17-dione); norboletone; norclostebol;
norethandrolone; oxabolone; oxandrolone; oxymesterone; oxymetholone;
prostanozol (17β-hydroxy-5α-androstano[3,2-c] pyrazole); quinbolone;

3 stanozolol; stenbolone; 1-testosterone (17β-hydroxy-5α-androst-1-en-3-
one); tetrahydrogestrinone (18a-homo-pregna-4,9,11-trien-17β-ol-3-one);
trenbolone and other substances with a similar chemical structure or similar
biological effect(s).
b. Endogenous** AAS when administered exogenously:
androstenediol (androst-5-ene-3β,17β-diol); androstenedione (androst-4-ene-
3,17-dione); dihydrotestosterone (17β-hydroxy-5α-androstan-3-one) ;
prasterone (dehydroepiandrosterone, DHEA); testosterone
and the following metabolites and isomers:
5α-androstane-3α,17α-diol; 5α-androstane-3α,17β-diol; 5α-androstane-
3β,17α-diol; 5α-androstane-3β,17β-diol; androst-4-ene-3α,17α-diol;
androst-4-ene-3α,17β-diol; androst-4-ene-3β,17α-diol; androst-5-ene-
3α,17α-diol; androst-5-ene-3α,17β-diol; androst-5-ene-3β,17α-diol;
4-androstenediol (androst-4-ene-3β,17β-diol); 5-androstenedione (androst-
5-ene-3,17-dione); epi-dihydrotestosterone; epitestosterone; 3α-hydroxy-
5α-androstan-17-one; 3β-hydroxy-5α-androstan-17-one; 19-
norandrosterone; 19-noretiocholanolone.
2. Other Anabolic Agents, including but not limited to:
Clenbuterol, selective androgen receptor modulators (SARMs), tibolone,
zeranol, zilpaterol.
For purposes of this section:
* “exogenous” refers to a substance which is not ordinarily capable of being
produced by the body naturally.
** “endogenous” refers to a substance which is capable of being produced by the
body naturally.
S2. PEPTIDE HORMONES, GROWTH FACTORS AND RELATED
SUBSTANCES
The following substances and their releasing factors are prohibited:
1. Erythropoiesis-Stimulating Agents [e.g. erythropoietin (EPO),
darbepoetin (dEPO), methoxy polyethylene glycol-epoetin beta
(CERA), hematide];
2. Chorionic Gonadotrophin (CG) and Luteinizing Hormone (LH) in
males;
3. Insulins;
4. Corticotrophins;
The Prohibited List 2010
19 September 2009
4
5. Growth Hormone (GH), Insulin-like Growth Factor-1 (IGF-1),
Mechano Growth Factors (MGFs), Platelet-Derived Growth Factor
(PDGF), Fibroblast Growth Factors (FGFs), Vascular-Endothelial
Growth Factor (VEGF) and Hepatocyte Growth Factor (HGF) as well
as any other growth factor affecting muscle, tendon or ligament protein
synthesis/degradation, vascularisation, energy utilization, regenerative
capacity or fibre type switching;
6. Platelet-derived preparations (e.g. Platelet Rich Plasma, “blood
spinning”) administered by intramuscular route. Other routes of
administration require a declaration of Use in accordance with the
International Standard for Therapeutic Use Exemptions.
and other substances with similar chemical structure or similar biological
effect(s).
S3. BETA-2 AGONISTS
All beta-2 agonists (including both optical isomers where relevant) are prohibited
except salbutamol (maximum 1600 micrograms over 24 hours) and salmeterol by
inhalation which require a declaration of Use in accordance with the International
Standard for Therapeutic Use Exemptions.
The presence of salbutamol in urine in excess of 1000 ng/mL is presumed not to
be an intended therapeutic use of the substance and will be considered as an
Adverse Analytical Finding unless the Athlete proves, through a controlled
pharmacokinetic study, that the abnormal result was the consequence of the use
of a therapeutic dose (maximum 1600 micrograms over 24 hours) of inhaled
salbutamol.
S4. HORMONE ANTAGONISTS AND MODULATORS
The following classes are prohibited:
1. Aromatase inhibitors including, but not limited to: aminoglutethimide,
anastrozole, androsta-1,4,6-triene-3,17-dione
(androstatrienedione), 4-androstene-3,6,17 trione (6-oxo),
exemestane, formestane, letrozole, testolactone.
2. Selective estrogen receptor modulators (SERMs) including, but not
limited to: raloxifene, tamoxifen, toremifene.
3. Other anti-estrogenic substances including, but not limited to:
clomiphene, cyclofenil, fulvestrant.
The Prohibited List 2010
19 September 2009
5
4. Agents modifying myostatin function(s) including but not limited to:
myostatin inhibitors.
S5. DIURETICS AND OTHER MASKING AGENTS
Masking agents are prohibited. They include:
Diuretics, probenecid, plasma expanders (e.g. glycerol; intravenous
administration of albumin, dextran, hydroxyethyl starch and mannitol) and
other substances with similar biological effect(s).
Diuretics include:
Acetazolamide, amiloride, bumetanide, canrenone, chlorthalidone,
etacrynic acid, furosemide, indapamide, metolazone, spironolactone,
thiazides (e.g. bendroflumethiazide, chlorothiazide, hydrochlorothiazide),
triamterene, and other substances with a similar chemical structure or similar
biological effect(s) (except drosperinone, pamabrom and topical dorzolamide and
brinzolamide, which are not prohibited).
A Therapeutic Use Exemption for diuretics and masking agents is not valid if an
Athlete’s urine contains such substance(s) in association with threshold or subthreshold levels of an exogenous Prohibited Substance(s).

Well, there you go. Clear as day.

Bike Laws: State Law vs. City Code

I am completely confused. I live in Charlotte, NC. Like many cyclists everywhere, we constantly have run-ins with angry motorists honking and yelling for us to “get off the road” or “ride single file.” And of course we yell back that we have every right to be there blah, blah. Same ole story. Or is it?

The North Carolina Driver’s Handbook states that, “There is no law that requires bicyclists to ride single file, nor is there a law that gives cyclists the right to ride two or more abreast. “ Firstly, and slightly off subject, could NC have possibly been vaguer in defining the rules of the road? Secondly, from this, one can deduce that we are in fact allowed to take up the entire lane…responsibly. The handbook also says, “In North Carolina, the bicycle has the legal status of a vehicle. This means that bicyclists have full rights and responsibilities on the roadway and are subject to the regulations governing the operation of a motor vehicle.” That one’s pretty clear. From this I know that driving my bike on a sidewalk, for instance, is illegal because driving my car on the sidewalk is illegal. That gives me a pretty good understanding of what I can and can’t do on the road of NC, right? Not really.

Enter the City of Charlotte Bicycle Law Code which at first defines a vehicle as: “Every device…drawn upon a street or highway, except devices moved by human power.” So, a bike is not a vehicle. OK. Wait, what? I should finish the paragraph? Ah, there it is, “…bicycles shall be deemed vehicles and every rider of a bicycle upon a highway shall be subject to the provisions of… the driver of a vehicle except those that by their nature can have no application.” So, a cyclist is considered a vehicle…except when it’s not. That's not confusing at all. So, when it’s on the street, it’s a vehicle, but when it’s on the sidewalk it’s not? And I know I can ride on the sidewalk because the code says it: “It is stressed that bicycles may be operated on sidewalks in the city except where expressly prohibited by posted signs.” That’s not what NC Law says.

I’ll spare you the jargon of the next one and just paraphrase Sec. 15-139 which pertains to traffic. Within Charlotte boundaries, cyclists are required to ride single file which clearly differs from the State Law.

So, now, we all, cyclists and motorists, just need to know exactly which roads fall under NC law and which fall under Charlotte code. Oh, and it’s all probably going to change when you go one town over. No sweat. A typical ride only takes me through about 8 different towns and the city/town limits are clearly marked with brightly colored lines and signs posted with the law clearly stated, so I know exactly which rules to follow. What? You mean there are no markings? No signs? But, I took the test. I passed with a 100%. NC issued me my Driver License. They didn’t happen to mention that the laws have a tendency to change every few miles I drive.

There is too much animosity on the roads. Is it any wonder? The laws contradict themselves and are written so vaguely that there is no clear right and wrong. With more and more people heading out on their bikes (the populartiy of cycling is growing exponentially) maybe it's time to clear up some of these vague laws and come up with just ONE set of rules so there’s no confusion.

Wednesday, October 7, 2009

Yes, I realize it's been a while. I've done it on purpose. It's the end of the season and I've taken a little time off the bike and off the blogoshpere. Don't cry, I'll start writing again soon when I grow tired of sitting on the couch, drinking beer and getting fat. 'Til then, cheers!