Thursday, October 22, 2009

Here's the List. Don't Screw Up.

Doping in sport is pretty cut and dry, right? I mean, they either did it or didn't. WADA (World Anti-Doping Association) has released the 2010 Banned Substance list. Can you keep up? Here it is:

PROHIBITED SUBSTANCES
S1. ANABOLIC AGENTS
Anabolic agents are prohibited.
1. Anabolic Androgenic Steroids (AAS)
a. Exogenous* AAS, including:
1-androstendiol (5α-androst-1-ene-3β,17β-diol ); 1-androstendione (5α-
androst-1-ene-3,17-dione); bolandiol (19-norandrostenediol); bolasterone;
boldenone; boldione (androsta-1,4-diene-3,17-dione); calusterone;
clostebol; danazol (17α-ethynyl-17β-hydroxyandrost-4-eno[2,3-d]isoxazole);
dehydrochlormethyltestosterone (4-chloro-17β-hydroxy-17α-methylandrosta-
1,4-dien-3-one); desoxymethyltestosterone (17α-methyl-5α-androst-2-en-
17β-ol); drostanolone; ethylestrenol (19-nor-17α-pregn-4-en-17-ol);
fluoxymesterone; formebolone; furazabol (17β-hydroxy-17α-methyl-5α-
androstano[2,3-c]-furazan); gestrinone; 4-hydroxytestosterone (4,17β-
dihydroxyandrost-4-en-3-one); mestanolone; mesterolone; metenolone;
methandienone (17β-hydroxy-17α-methylandrosta-1,4-dien-3-one);
methandriol; methasterone (2α, 17α-dimethyl-5α-androstane-3-one-17β-ol);
methyldienolone (17β-hydroxy-17α-methylestra-4,9-dien-3-one); methyl-1-
testosterone (17β-hydroxy-17α-methyl-5α-androst-1-en-3-one);
methylnortestosterone (17β-hydroxy-17α-methylestr-4-en-3-one);
methyltestosterone; metribolone (methyltrienolone, 17β-hydroxy-17α-
methylestra-4,9,11-trien-3-one); mibolerone; nandrolone; 19-
norandrostenedione (estr-4-ene-3,17-dione); norboletone; norclostebol;
norethandrolone; oxabolone; oxandrolone; oxymesterone; oxymetholone;
prostanozol (17β-hydroxy-5α-androstano[3,2-c] pyrazole); quinbolone;

3 stanozolol; stenbolone; 1-testosterone (17β-hydroxy-5α-androst-1-en-3-
one); tetrahydrogestrinone (18a-homo-pregna-4,9,11-trien-17β-ol-3-one);
trenbolone and other substances with a similar chemical structure or similar
biological effect(s).
b. Endogenous** AAS when administered exogenously:
androstenediol (androst-5-ene-3β,17β-diol); androstenedione (androst-4-ene-
3,17-dione); dihydrotestosterone (17β-hydroxy-5α-androstan-3-one) ;
prasterone (dehydroepiandrosterone, DHEA); testosterone
and the following metabolites and isomers:
5α-androstane-3α,17α-diol; 5α-androstane-3α,17β-diol; 5α-androstane-
3β,17α-diol; 5α-androstane-3β,17β-diol; androst-4-ene-3α,17α-diol;
androst-4-ene-3α,17β-diol; androst-4-ene-3β,17α-diol; androst-5-ene-
3α,17α-diol; androst-5-ene-3α,17β-diol; androst-5-ene-3β,17α-diol;
4-androstenediol (androst-4-ene-3β,17β-diol); 5-androstenedione (androst-
5-ene-3,17-dione); epi-dihydrotestosterone; epitestosterone; 3α-hydroxy-
5α-androstan-17-one; 3β-hydroxy-5α-androstan-17-one; 19-
norandrosterone; 19-noretiocholanolone.
2. Other Anabolic Agents, including but not limited to:
Clenbuterol, selective androgen receptor modulators (SARMs), tibolone,
zeranol, zilpaterol.
For purposes of this section:
* “exogenous” refers to a substance which is not ordinarily capable of being
produced by the body naturally.
** “endogenous” refers to a substance which is capable of being produced by the
body naturally.
S2. PEPTIDE HORMONES, GROWTH FACTORS AND RELATED
SUBSTANCES
The following substances and their releasing factors are prohibited:
1. Erythropoiesis-Stimulating Agents [e.g. erythropoietin (EPO),
darbepoetin (dEPO), methoxy polyethylene glycol-epoetin beta
(CERA), hematide];
2. Chorionic Gonadotrophin (CG) and Luteinizing Hormone (LH) in
males;
3. Insulins;
4. Corticotrophins;
The Prohibited List 2010
19 September 2009
4
5. Growth Hormone (GH), Insulin-like Growth Factor-1 (IGF-1),
Mechano Growth Factors (MGFs), Platelet-Derived Growth Factor
(PDGF), Fibroblast Growth Factors (FGFs), Vascular-Endothelial
Growth Factor (VEGF) and Hepatocyte Growth Factor (HGF) as well
as any other growth factor affecting muscle, tendon or ligament protein
synthesis/degradation, vascularisation, energy utilization, regenerative
capacity or fibre type switching;
6. Platelet-derived preparations (e.g. Platelet Rich Plasma, “blood
spinning”) administered by intramuscular route. Other routes of
administration require a declaration of Use in accordance with the
International Standard for Therapeutic Use Exemptions.
and other substances with similar chemical structure or similar biological
effect(s).
S3. BETA-2 AGONISTS
All beta-2 agonists (including both optical isomers where relevant) are prohibited
except salbutamol (maximum 1600 micrograms over 24 hours) and salmeterol by
inhalation which require a declaration of Use in accordance with the International
Standard for Therapeutic Use Exemptions.
The presence of salbutamol in urine in excess of 1000 ng/mL is presumed not to
be an intended therapeutic use of the substance and will be considered as an
Adverse Analytical Finding unless the Athlete proves, through a controlled
pharmacokinetic study, that the abnormal result was the consequence of the use
of a therapeutic dose (maximum 1600 micrograms over 24 hours) of inhaled
salbutamol.
S4. HORMONE ANTAGONISTS AND MODULATORS
The following classes are prohibited:
1. Aromatase inhibitors including, but not limited to: aminoglutethimide,
anastrozole, androsta-1,4,6-triene-3,17-dione
(androstatrienedione), 4-androstene-3,6,17 trione (6-oxo),
exemestane, formestane, letrozole, testolactone.
2. Selective estrogen receptor modulators (SERMs) including, but not
limited to: raloxifene, tamoxifen, toremifene.
3. Other anti-estrogenic substances including, but not limited to:
clomiphene, cyclofenil, fulvestrant.
The Prohibited List 2010
19 September 2009
5
4. Agents modifying myostatin function(s) including but not limited to:
myostatin inhibitors.
S5. DIURETICS AND OTHER MASKING AGENTS
Masking agents are prohibited. They include:
Diuretics, probenecid, plasma expanders (e.g. glycerol; intravenous
administration of albumin, dextran, hydroxyethyl starch and mannitol) and
other substances with similar biological effect(s).
Diuretics include:
Acetazolamide, amiloride, bumetanide, canrenone, chlorthalidone,
etacrynic acid, furosemide, indapamide, metolazone, spironolactone,
thiazides (e.g. bendroflumethiazide, chlorothiazide, hydrochlorothiazide),
triamterene, and other substances with a similar chemical structure or similar
biological effect(s) (except drosperinone, pamabrom and topical dorzolamide and
brinzolamide, which are not prohibited).
A Therapeutic Use Exemption for diuretics and masking agents is not valid if an
Athlete’s urine contains such substance(s) in association with threshold or subthreshold levels of an exogenous Prohibited Substance(s).

Well, there you go. Clear as day.

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